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Funding; Research; Innoation; Brad Feld; 3/31/08 - PHOTOS & Events

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DUE - 3/31/08 M TechStars: Applications Closing Today
4/1-4/08 T-F - Day Marpa Ctr, Naropa: Gearing Up for Business Sustainability
4/1/08 T - 11:30 ACG Luncheon: Both Sides of Equation - Raising Capital
4/1/08 T - PM Boulder, Denver New Technology Meetup
4/2/08 W Noon ViaWest: Lunch & Learn
4/7-10/08 M-Th 24th National Space Symposium
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4/7/08 M - PM DaVinci Institute: Night With A Futurist
4/8/08 T - PM RVC: Pathway to Entrepreneurship, Challenges & Choices
4/9/08 W - AM SBIR Colorado and CORE: Early Stage Financing
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4/15/08 W - PM MARPA Center:Leadership in a Multicultural Age
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Paul Bunn, Jr., M.D., Director, University of  CO Cancer Center465_ Developing Novel Cancer Therapies and Understanding the Patient Outcomes
There are four main types of cancer. About 85% are non-small cell types and the balance small cell, that often identifies lung cancer. Larry visited and interviewed Dr. Paul Bunn, Jr., Professor of Medicine and Director, University of Colorado Cancer Center as well as holding the James Dudley Endowed Chair of Lung Cancer Research. Dr. Bunn was recently awarded the 'Inventor of the Year, Denver, by the University of Colorado Tech Transfer Office (CU TTO). CU TTO is very often the conduit that helps bring great research and innovative ideas from the bench to the benefit of the general public. Dr. Bunn spoke to the community as a whole, offered some easy to understand explanations for the lay person. People often identify surgery and drugs as the ways of dealing with cancer issues. Dr. Bunn discusses the targets of new cancer therapies and how they are identified. He also shines light on how drugs that attack these targets are discovered and produced. Dr. Bunn describes how clinical trials are done and what preclinical information is needed. The success rate is described as potentially 2 out of 3. Dr. Bunn works with federal agencies, professional associations, universities as well as private sector companies such as Apoplogic. You will learn how new cancer drugs are developed and tested including how long it takes, how much it costs, the pitfalls, and success rates. Outcomes for cancer patients are discussed.

Related Links: University of Colorado Cancer Center || Apoplogic || CU TTO || Podcast Directory || BYTES: 26255028 - 3/31/08 Keywords: Dr. Paul Bunn, Cancer Research, Clinical Testing, University of Colorado Tech Transfer Office
Brad Feld, Foundry GroupBrad Feld - TechStars Closing Applications Today!
Brad Feld talks about the mentoring that the TechStars receive. It fills the experience gap by bringing together the best and the brightest in one place and surrounding them with incredible proven mentors for the summer. With this much talent in one place you’ll get great advice on your product and strategy, thereby ensuring the best possible start for your new business. Did we mention funding? Seed funding? TechStars fills the startup funding gap by providing just enough capital to get your idea off the ground. Your new company receives up to $15,000 in seed funding. Application Due Date: March 31, 2008.

Related Links: TechStars Details || TechStars Mentors || TechStars Blog || Feld Thoughts || KEYWORDS: Brad Feld, David Cohen, TechStars, Entrepreneurs, Mentors, Funding Bytes: 25745766
What is ColoradoFIRST? What was all the excitement about?
5th ColoradoFIRST Regional Competition at DU's Ritchie Center, Magness ArenaThe FIRST Robotics Competition stages short games played by autonomous and remote controlled robots. It is a unique varsity sport of the mind designed to help high school students discover how interesting and rewarding the life of engineers and scientists can be. FIRST was founded in 1989 by Dean Kamen, inventor of the Segway Human Transporter and President of DEKA Research Development Corporation based in Manchester, New Hampshire. In Colorado we have 30 active teams. The excitement and enthusiasm rivals any sports event. The teamwork and commoradere can't be matched. Take a look at our judges, you'll see high ranking representatives from the Colorado Technology community, including w3w3® ! w3w3® captured the two day event in photo albums - It's an experience that will live on and change your future. Come take a look at our future inventors, engineers, scientists and great kids!
Photo Albums Found Here

Related Links: Colorado FIRST || Segway || US FIRST || Find It || KEYWORDS: Colorado FIRST, Dean Kamen, US FIRST, Regional Robotics Competition, Innovation, Youth

461_ Leadership and the Culture of Commitment and Sustainability
Dan Montgomery, Blue Opal Strategiesenclosure-voice There are a lot of people doing a lot of work, more of an engineering process perspective. That is where do things come from, how do they get used, what happens when we’re done using it. So there’s a lot of good work going on at the material level," explains Dan Montgomery, Marpa Center for Business & Economics. What we are emphasizing is what kind of state-of-mind, of leadership, of organizational culture goes with creating a sustainable world. It’s the kind of inner dimension and the social dimension that supports being more responsible in the way that we use the earth’s resources. When we look at business decisions we have a much longer and broader view of the impacts we are having. It’s allowing more stakeholders into the picture, having a longer timeline, thinking about what happens to your product when people are done using it. Business schools 25 years ago taught that business decision making was a zero sum game. There were tough trade-offs involved. The ultimate rationale was shareholder value. Today, other groups that we would call stakeholders such as the communities in which we operate, the communities in which our supply chain operate, were really not a concern before, because they weren’t in the decision making equation. If you talk with today’s business students, they’re starting off with the idea that sustainability is a value that’s just table stakes to be in the game. Collaboration is where we get into talking about culture and commitment. The cycle of commitment, helping people look at this area of agreements and commitments. People are not operating in corporate silos anymore. We’re all dealing with a lot of lateral pier relationships, joint ventures; the business environment is much more complex now than it was a generation ago. What we’re doing in this seminar in June at Naropa, is introducing some methods for looking at that entire web or network of stakeholders and understanding what all the trade-offs and value exchanges are. It gives us a better way of to think about the environment that we operate in. LISTEN Bytes: 25760812 - 3/24/08
Related Links: Business Sustainability || Business and Economics || Leading Through Conflict || Authentic Leadership || Blue Opal Strategies || Keywords: Dan Montgomery, Marpa Center, Business, Economics, Sustainable, Blue Opal Strategies

459_ Software as a Service (SaaS) Meets Software for Security (SfS)
Gerhard Eschelbeck, CTO & Sr. VP, Engineering, Webrootenclosure-voice Gerhardt Eschelbeck is the CTO and Senior Vice President of Engineering, at Webroot. Gerhardt is one of the first in the country, maybe the world, to deal with the SaaS model. That’s Software as a Service. This has been a significant transition which has been driven largely by the threat landscape. Today’s threat is fairly stealth and designed to stay undetected for as long a time as possible. The purpose of the thieves is financially motivated. Today’s threats are fundamentally designed to steal information from the user’s computer, the banking information, financial, health information and what not. Therefore, we clearly have to look at this from a protection standpoint. I think the technologies that we developed 10 and 15 years ago which were very effective when applied to the virus threat, are not as applicable for today’s threat. What the industry requires is an approach that is much more sophisticated. We have moved from a purely desktop approach to a multi tiered defense model. I think the goal here is that you need to use a leverage similar to what the bad guys are using to actually detect those spyware technologies. This is where Webroot has been pioneering and working as an organization over the past four years. We have been able to protect, prevent and detect infections for our customers; this is certainly our top priority. Steps that an organization can do to stay clean and healthy from a computer hygiene perspective are; First make sure you update your systems whenever patches become available. “Microsoft Tuesday”. Missing patches are very frequently used within the first 24 – 48 hours by hackers to take advantage of those security holes. Not just the Microsoft programs, but all of the other programs and systems that you use, be it iTunes or Adobe, etc. The Second Recommendation: Make sure that your malware protection is the latest, state-of-the-art, and is updated to the minute. Thirdly, there are typically areas of very sensitive data that you have on your computer. Take a look at that from an encryption perspective, to make sure it is protected properly. 3/24/08 Bytes: 21176636
Related Links: Webroot || E-Mail Security || On Demand Software || Cyber Security || Podcast Directory || Keywords: Gerhardt Eschelbeck, Webroot, SaaS, SfS, user’s computer, banking information, financial, health information, computer virus, malware

 

466_ Moving From an Innovative Idea to Commercialization
Jeff Richardson, Living Systems Have you ever wondered how you could get money for a high-risk innovative idea. Jeff Richardson, President of Living Systems explains how. Learn how small technology companies can access substantial funding from the federal government. This is the funding that can pay for high-risk R&D. Jeff explains that the processes are clear, complete, and fair. But it is also highly competitive, scientifically rigorous, and extremely time-consuming. However, the process forces you to think through your technology and its commercial potential...the latter is a requirement of the SBIR program. Because of the competitiveness and long time frames, companies pursuing SBIR funds are advised to have a “ladder” of proposals in the pipeline. Jeff answers these questions about the federal grant program, Small Business Innovative Research program (SBIR). Why is your company interested in SBIR money? How do you apply for SBIR funding? How is the SBIR funding working out (Both the Pros & the Cons)? Where does it all lead? Jeff shares a number of tips that could help you and your innovative company get a federal grant...it's money you don't have to pay back.

Related Links: Living Systems || NIH Grants || SBIR Colorado || Looking for Money || BYTES: 23521387 - 3/31/08 KEYORDS: Jeff Richardson, Living Systems, SBIR, Small Business Innovative Research, Commercialize, Innovation, R&D
Dean Kamen, Demonstrating the "stair climbing wheelchair" 464_ This Could Be the FIRST Step to Bringing Out Innovation in Our Youth
In September 2002, CSIA invited Dean Kamen, founder of FIRST and President of DEKA Research and Development to talk about innovation. While Dean is too humble to claim this, many call him the the father of innovation spirit. At the event, Dean Kamen entered the Seawell Ballroom in what looked like a motorized wheelchair. The wheelchair proceeded to 'walk' up the stairs of the stage, over to the podium and then the wheelchair proceeded to lift Dean at a level that would be comparable to a 6' 6" person. The audience was amazed and listened to his humorous and insightful talk. After a little discussion, one of Dean's teammates brought up on stage what is now widely known as the Segway. The first few seconds of this unedited recording you'll hear Dean on his high-tech wheelchair climbing the stairs of the stage onto the podium. Dean goes onto point out that, "Many youth are are inspired to be a Michael Jordan, but it's more likely they will end up flipping hamburgers." That's a tough sentence for parents and grandparents to hear, but unless there is a change, you know the rest of the story. Dean Kamen and FIRST offer an exciting alternative...and now we have Colorado FIRST. Larry and Pat along with grandchildren (and hundreds of others) recently attended the Colorado FIRST Regional Competition held at DU. It was the most exciting and uplifting event they have attended in decades. Listen to Dean Kamen's talk, take a look at the photos and visit their site...if you don't know what to do next, give us a call. VIEW Photo Album from Dean Kamen's Visit

Related Links: Colorado FIRST || Segway || US FIRST || Find It || 3/31/08 BYTES: 78314164 - Listen Part 1 of 2
BYTES: 79476927 - Listen Part 2 of 2

Paul Grimmer, 
                President,  Eltron Research and Development 462_ Commercialization of Innovative Ideas - Far Reaching and Profitable
enclosure-voice Eltron Research & Development is one of the largest SBIR companies in the country. Paul Grimmer came out of big business; he worked for Conoco and Conoco Phillips for almost 30 years, and never dealt with SBIR, because it’s for small businesses. About 2 ½ years ago Paul and his wife bought Eltron Research. “Eltron had developed over 100 technologies that we thought had commercial value”, Paul said. But the focus was, ‘let’s get the next project’, not taking the one you finished and going to the market place with it. The big challenge is, there are very few projects ready to go to market after completing a phase two SBIR program ($850K). Some of them may require ½ million, a million, some may require a hundred million dollars, but the key is, there’s no more money from the feds. You’re too early for the VCs, less for the angels who generally don’t understand a lot of the technologies. So, how do we get all this, or at least a significant fraction of these technologies to market? This is really what the SBIR program is all about, to help the small businesses get a jump start in getting their innovations to the market. Classically most SBIR companies are focused on science and maybe to a lesser degree engineering. So, we’ve added engineers, business developers, and of course all this costs money outside of SBIR. So that’s a challenge, just getting the right skill sets in there to help analyze and develop things, and so forth. So how do you bridge that gap? Well, we’ve elected to go down two routes, one (longer term) is to find larger companies in the industry that have deeper pockets that might be interested in forming a new product line or enhancing a product that they’ve got. You work a deal with them and in return for them funding additional development they retain the rights to your technology. Some of that can take a long time. The other thing we’ve done, since I’m not interested in giving away huge chunks of our technology, at least until we get them into the market place, has been to do some things so that we can continue the development ourselves.
Related Links: Eltron Research & Development || SBIR Sources of Info || Looking for Money || w3w3® Blog || Keywords: Paul Grimmer, Eltron, Research, Development, SBIR, Research, Commercialization, Innovative, Grants 3/24/08 - Bytes: 25745766

Frank Amoroso, SVB > Silicon Valley Bank460_ Silicon Valley Bank and the Clean Tech Investment Space
enclosure-voice “Let’s take a step back and talk about the difference between debt and equity – they both have their own uses. You should be financing assets with debt. Equity, you can finance either expenses or assets,” points out Frank Amoroso of the Silicon Valley Bank. He goes onto say, “However if you have worked hard and sold a portion of your company to raise equity, if you don’t have to, you shouldn’t use those equity dollars to finance assets, if you can get debt dollars to do so. And then you take a look at the company’s balance sheet and income statement. If the company has balance sheet strength they should be able to qualify for some kind of debt. Absent balance sheet strength or P&L strength, really what you’re talking about is equity. As a federally regulated banking institution, we like to think of ourselves as quite a bit different than the other 8000 banks in the US. Clean tech area is hot and Frank is one of three individuals across the nation dedicated to clean tech practice. ). “Definitely clean tech is hot, sustainability is hot, you get the sense that more and more investors are stretching to look into this market sector. The way that SVB is looking at that is going to be an extension of our historical model. That is to leverage that equity investment with debt. The right amount of debt, every company has its own balance of debt vs. equity, there is a correct number. We’re really more focused on the tech part of clean tech, disruptive intellectual property, professional equity sponsorship, if a company has both of those in the clean tech space, then we’ll be able to do even more than we’ve historically been able to do. If on the other hand the technology is a great efficiency plan, installing all new solar panels, or it’s maybe a lighting technology, you know, still interested. Can we be as aggressive? Can we get in as early, do as many things? Probably not, because our historical model has been to truly leverage that professional equity sponsorship.” Frank also addresses potential challenges including the credit crunch and the high-tech bubble reoccurrence.
Related Links: Silicon Valley Bank || Conscious Economy || Venture Capital || Find It || Keywords: Frank Amoroso, Silicon Valley Bank, Green Tech, Clean Tech, Debt, Equity, Investing, Finance, Assets, Bank, Technology, Bioscience Bytes: 25231676 - 3/24/08
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